Arthritogenic alphaviruses: new insights into arthritis and bone pathology. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Chen, Weiqiang; Foo, Suan-Sin; Sims, Natalie A.; Herrero, Lara J.; Walsh, Nicole C.; Mahalingam, Suresh
• Is Part Of: Trends in microbiology. Volume 23:Issue 1(2015)
• Page Start: 35
• Page End: 43
• Publication Date: 2015-01
• Subjects: Microbiology -- Periodicals; Infection -- Periodicals; Virulence (Microbiology) -- Periodicals; Infection -- Periodicals; Microbiology -- Periodicals; Virulence -- Periodicals; Microbiologie -- Périodiques; Infection -- Périodiques; Virulence (Microbiologie) -- Périodiques; Infection; Microbiology; Virulence (Microbiology); 579
• DOI: 10.1016/j.tim.2014.09.005
• Languages: English
• ISSNs: 0966-842X

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Enhanced osteoclastogenesis and bone loss take place during arthritogenic alphavirus infection.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">There is strong interplay between immune responses in alphaviral arthritis and bone health.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">There is a potential risk of alphavirus infection exacerbating underlying inflammatory arthritis.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Targeting osteotropic factors may be efficacious in treating alphaviral-induced bone loss.</p> </list-item> </list> </p> </sec> </abstract>