The promoter of the white spot syndrome virus immediate-early gene WSSV108 is activated by the cellular KLF transcription factor. Issue 1 (March 2015)

• Record Type: Journal Article
• Authors: Liu, Wang-Jing; Lo, Chu-Fang; Kou, Guang-Hsiung; Leu, Jiann-Horng; Lai, Ying-Jang; Chang, Li-Kwan; Chang, Yun-Shiang
• Is Part Of: Developmental and comparative immunology. Volume 49:Issue 1(2015)
• Page Start: 7
• Page End: 18
• Publication Date: 2015-03
• Subjects: Immunology -- Periodicals; Developmental immunology -- Periodicals; 616.079
• DOI: 10.1016/j.dci.2014.10.015
• Languages: English
• ISSNs: 0145-305X

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010"> <italic>WSSV108</italic> has high expression levels throughout the WSSV infection cycle.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">WSSV108 is likely to act as a transcriptional factor.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020"> <italic>WSSV108</italic> promoter has a Krüppel-like factor (KLF) binding site.</p> </list-item> <list-item id="u0025"> <label></label> <p id="p0025">Shrimp KLF plays a major role in <italic>WSSV108</italic> promoter activity.</p> </list-item> <list-item id="u0030"> <label></label> <p id="p0030">Silencing of KLF in <italic>L. vannamei</italic> reduces <italic>WSSV108</italic> expression and WSSV replication.</p> </list-item> </list> </p> </sec> </abstract>