Recombinant goldfish thrombopoietin up-regulates expression of genes involved in thrombocyte development and synergizes with kit ligand A to promote progenitor cell proliferation and colony formation. Issue 1 (March 2015)

• Record Type: Journal Article
• Authors: Katakura, Fumihiko; Katzenback, Barbara A.; Belosevic, Miodrag
• Is Part Of: Developmental and comparative immunology. Volume 49:Issue 1(2015)
• Page Start: 157
• Page End: 169
• Publication Date: 2015-03
• Subjects: Immunology -- Periodicals; Developmental immunology -- Periodicals; 616.079
• DOI: 10.1016/j.dci.2014.11.001
• Languages: English
• ISSNs: 0145-305X

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010"> <italic>tpo</italic> was highly expressed in heart, followed by spleen, liver, brain, intestine, and kidney tissues.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">Recombinant goldfish TPO up-regulated expression of genes involved in thrombocyte development.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020">rgTPO synergized with recombinant goldfish kit ligand A (rgKITLA) to promote progenitor cell proliferation and thrombocytic colony-formation.</p> </list-item> </list> </p> </sec> </abstract>