Malignant pleural mesothelioma: New hope in the horizon with novel therapeutic strategies. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Remon, J.; Reguart, N.; Corral, J.; Lianes, P.
• Is Part Of: Cancer treatment reviews. Volume 41:Issue 1(2015)
• Page Start: 27
• Page End: 34
• Publication Date: 2015-01
• Subjects: Cancer -- Periodicals; Cancer -- Treatment -- Periodicals; Neoplasms -- therapy -- Periodicals; Cancer -- Périodiques; Cancer -- Traitement -- Périodiques; Cancer -- Treatment; Electronic journals; Periodicals; 616.99406
• DOI: 10.1016/j.ctrv.2014.10.007
• Languages: English
• ISSNs: 0305-7372

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st085">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0210">Malignant pleural mesothelioma (MPM) incidence has increased and it is not expected to drop until 2015 and 2030.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0215">Germline mutations could help identifying individuals at high risk of MPM who could be targeted for early intervention.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0220">Molecular landscape and identification of deregulated pathways may help to achieve a customized therapy in MPM.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0225">FAK inhibitors, antiangiogenic therapies, NGR-hTNF are promising new therapies in MPM.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0230">Immunotherapy offers a promising activity in MPM.</p> </list-item> </list> </p> </sec> </abstract>