Comparison of the immunogenicity and safety of polysaccharide and protein-conjugated pneumococcal vaccines among the elderly aged 80 years or older in Japan: An open-labeled randomized study. Issue 2 (3rd January 2015)

• Record Type: Journal Article
• Authors: Namkoong, Ho; Funatsu, Yohei; Oishi, Kazunori; Akeda, Yukihiro; Hiraoka, Rika; Takeshita, Kei; Asami, Takahiro; Yagi, Kazuma; Kimizuka, Yoshifumi; Ishii, Makoto; Tasaka, Sadatomo; Suzuki, Yukio; Iwata, Satoshi; Betsuyaku, Tomoko; Hasegawa, Naoki
• Is Part Of: Vaccine. Volume 33:Issue 2(2015)
• Page Start: 327
• Page End: 332
• Publication Date: 2015-01-03
• Subjects: Vaccines -- Periodicals; 615.372
• DOI: 10.1016/j.vaccine.2014.11.023
• Languages: English
• ISSNs: 0264-410X

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0060"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0210">Increase in GMCs of serotype-specific IgG levels in PCV7 group.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0215">Increase in GMTs of OIs of serotype-specific IgG levels in PCV7 group.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0220">Our study confirmed the safety of both PCV7 and PPV23 vaccines in elderly people.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0225">PCV7 displayed superior immunogenicity than PPV23 in 4/7 serotypes included in PCV7.</p> </list-item> </list> </p> </sec> </abstract>