Intratumoral gene expression of 5-fluorouracil pharmacokinetics-related enzymes in stage I and II non-small cell lung cancer patients treated with uracil-tegafur after surgery: A prospective multi-institutional study in Japan. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Eguchi, Keisuke; Oyama, Takahiko; Tajima, Atsushi; Abiko, Tomohiro; Sawafuji, Makoto; Horio, Hirotoshi; Hashizume, Toshinori; Matsutani, Noriyuki; Kato, Ryoichi; Nakayama, Mitsuo; Kawamura, Masafumi; Kobayashi, Koichi
• Is Part Of: Lung cancer. Volume 87:Issue 1(2015:Jan.)
• Page Start: 53
• Page End: 58
• Publication Date: 2015-01
• Subjects: Lungs -- Cancer -- Periodicals; Lung Neoplasms -- Abstracts; Lung Neoplasms -- Periodicals; Poumons -- Cancer -- Périodiques; Lungs -- Cancer; Periodicals; Electronic journals; Electronic journals; 616.99424
• DOI: 10.1016/j.lungcan.2014.10.013
• Languages: English
• ISSNs: 0169-5002

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">We assessed gene expression levels of 5-FU related enzymes in stage I/II NSCLC.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Tumors from 236 patients with UFT administration after surgery were examined.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Thymidylate synthase gene expression was an independent predictive factor for DFS.</p> </list-item> </list> </p> </sec> </abstract>