51. Median and tibial nerve somatosensory evoked potentials study in a group of 60 achondroplasic children: Correlation to maturational and statural data. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Fornarino, S.; Rossi, D.P.; Allegri, A.; Doria Lamba, L.; Lanteri, P.
• Is Part Of: Clinical neurophysiology. Volume 126:Issue 1(2015:Jan.)
• Page Start: e12
• Publication Date: 2015-01
• Subjects: Neurophysiology -- Periodicals; Electroencephalography -- Periodicals; Electromyography -- Periodicals; Neurology -- Periodicals; 612.8
• DOI: 10.1016/j.clinph.2014.10.070
• Languages: English
• ISSNs: 1388-2457

Abstract

<abstract xml:lang="en" abstract-type="author" id="ab005"> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <p id="sp005">To evaluate the role of median and tibial nerve SEPs for foramen magnum and lumbar stenosis assessment in achondroplasic children. We reviewed SEPs recorded in 60 achondroplasic patients aged from 21 days to 17 years, followed-up from 2007. Forty-two of our patients underwent to neurosurgical intervention for cervical (30/42) and lumbar (13/42) decompression. We analyzed peak latencies of P37 for lower limbs, N11, N13, P14 and N20 and the interpeak latencies (IPLs) N13-N20 for upper limbs, related to 5 age groups (&lt;1 year, ⩾1–3, ⩾3–5, ⩾5–9, ⩾9 years) and height. The peak latencies of P37, N11, N13 and P14 progressively increased with age. The peak latencies of N20 decreased exponentially with age during the first three years of age then increased with height after the age of 9 years (U-shaped). The IPLs N13-N20 decreased exponentially with age. The cortical waveforms P37 were often very broad in the youngest subjects and sometimes difficult to measure. In our patients, the N20 latencies are affected by age and height by opposing factors, but no P37. The earlier impairment of tibial than median nerve SEPs in achondroplasic patients has to be correlated with neuroradiological findings of spinal cord compression.</p> </sec> </abstract>