36. Isolated monophasyc whyte matter lesion: Neoplasm or tumefactive MS?. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Stipa, G.; Frondizi, D.; Moschini, E.; Di Schino, C.; Galletti, F.; Principi, M.; Aprile, I.; Conti, C.; Rossi, V.; Fattori, P.; Mancini, A.; Roscini, N.; Carletti, S.
• Is Part Of: Clinical neurophysiology. Volume 126:Issue 1(2015:Jan.)
• Page Start: e9
• Publication Date: 2015-01
• Subjects: Neurophysiology -- Periodicals; Electroencephalography -- Periodicals; Electromyography -- Periodicals; Neurology -- Periodicals; 612.8
• DOI: 10.1016/j.clinph.2014.10.055
• Languages: English
• ISSNs: 1388-2457

Abstract

<abstract xml:lang="en" abstract-type="author" id="ab005"> <title> <x xml:space="preserve">Abstract</x> </title> <sec> <p id="sp005">Isolated monophasyc whyte matter lesion could have a demyelinating or neoplastic origin. A 26 years old woman, at the 6th week of pregnancy, acutely presented motor deficit to the right side, and aphasia. MRI showed a left temporal lesion in the subcortical white matter, without edema, and with dishomogeneous enhancement. Spectroscopic MR pointed out a choline increase, and a reduction of NAA peak. Visual evoked potential showed peculiar cortical response, while liquoral exam showed oligoclonal bands. Steroid treatment produced a substantial clinical and radiological stability. After miscarriage, the patient underwent brain biopsy, which in this case was the gold standard for diagnosis.</p> </sec> </abstract>