Hyaluronan regulates chemical allergen-induced IL-18 production in human keratinocytes. Issue 1 (5th January 2015)

• Record Type: Journal Article
• Authors: Nikitovic, Dragana; Berdiaki, Aikaterini; Galbiati, Valentina; Kavasi, Rafaela-Maria; Papale, Angela; Tsatsakis, Aristidis; Tzanakakis, George N.; Corsini, Emanuela
• Is Part Of: Toxicology letters. Volume 232:Issue 1(2015)
• Page Start: 89
• Page End: 97
• Publication Date: 2015-01-05
• Subjects: Toxicology -- Periodicals; 363.179
• DOI: 10.1016/j.toxlet.2014.09.026
• Languages: English
• ISSNs: 0378-4274

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0035"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">IL-18 has a key role in allergic contact dermatitis progression.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Contact allergens enhance hyaluronan (HA) degradation in keratinocytes.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Modulation of HA content reduces IL-18 production.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Oxidative stress is involved in HA degradation and IL-18 production.</p> </list-item> <list-item id="lsti0025"> <label></label> <p id="par0025">HA fragments are mediators in contact sensitisation process.</p> </list-item> </list> </p> </sec> </abstract>