17-beta estradiol inhibits oxidative stress-induced accumulation of AIF into nucleolus and PARP1-dependent cell death via estrogen receptor alpha. Issue 1 (5th January 2015) - Batnasan, Enkhzaya
Highlights Estrogen inhibits H2O2-induced PARP1 activation and nuclear fragmentation. Estrogen blocks H2O2-induced AIF translocation to nucleoli. Estrogen protects MCF-7 cells from H2O2-induced cell death. Estrogen receptor alpha mediates the protective role of estrogen.