Combined effects of current-smoking and the aldehyde dehydrogenase 2*2 allele on the risk of myocardial infarction in Japanese patients. Issue 1 (5th January 2015) - Morita, Kazunori
Highlights Aldehyde dehydrogenase 2 (ALDH2) detoxifies toxic aldehydes in cigarette smoke. Current-smoking ALDH2*2 allele carriers were at risk of myocardial infarction (MI). Current-smoking and ALDH2*2 synergistically increased the peak creatine kinase. Current-smoking and ALDH2*2 synergistically increased triglycerides in MI subjects.