Metallothionein isoform 3 expression in human skin, related cancers and human skin derived cell cultures. Issue 1 (5th January 2015)

• Record Type: Journal Article
• Authors: Slusser, Andrea; Zheng, Yun; Zhou, Xu Dong; Somji, Seema; Sens, Donald A.; Sens, Mary Ann; Garrett, Scott H.
• Is Part Of: Toxicology letters. Volume 232:Issue 1(2015)
• Page Start: 141
• Page End: 148
• Publication Date: 2015-01-05
• Subjects: Toxicology -- Periodicals; 363.179
• DOI: 10.1016/j.toxlet.2014.09.028
• Languages: English
• ISSNs: 0378-4274

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0035"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Skin is a target site of As⁺³ toxicity.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Metallothionein-3 (MT3) is highly expressed in human skin.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Skin-derived malignancies also expressed MT3.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Suggested that MT3 is a major sulfhydryl source for dermal As⁺³ binding.</p> </list-item> </list> </p> </sec> </abstract>