MicroRNA-21, up-regulated by arsenite, directs the epithelial–mesenchymal transition and enhances the invasive potential of transformed human bronchial epithelial cells by targeting PDCD4. Issue 1 (5th January 2015)

• Record Type: Journal Article
• Authors: Luo, Fei; Ji, Jie; Liu, Yi; Xu, Yuan; Zheng, Gang; Jing, Jinfei; Wang, Bairu; Xu, Wenchao; Shi, Le; Lu, Xiaolin; Liu, Qizhan
• Is Part Of: Toxicology letters. Volume 232:Issue 1(2015)
• Page Start: 301
• Page End: 309
• Publication Date: 2015-01-05
• Subjects: Toxicology -- Periodicals; 363.179
• DOI: 10.1016/j.toxlet.2014.11.001
• Languages: English
• ISSNs: 0378-4274

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0055"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">miR-21 inactivates Twist1 via up-regulation of PDCD4.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">miR-21 is involved in arsenite-induced epithelial–mesenchymal transition.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">miR-21-mediated EMT promotes the migration and invasion of arsenite-transformed cells.</p> </list-item> </list> </p> </sec> </abstract>