Prevention of irinotecan induced diarrhea by probiotics: A randomized double blind, placebo controlled pilot study. Issue 3 (June 2015)

• Record Type: Journal Article
• Authors: Mego, Michal; Chovanec, Jozef; Vochyanova-Andrezalova, Iveta; Konkolovsky, Peter; Mikulova, Milada; Reckova, Maria; Miskovska, Vera; Bystricky, Branislav; Beniak, Juraj; Medvecova, Lenka; Lagin, Adela; Svetlovska, Daniela; Spanik, Stanislav; Zajac, Vladimir; Mardiak, Jozef; Drgona, Lubos
• Is Part Of: Complementary therapies in medicine. Volume 23:Issue 3(2015)
• Page Start: 356
• Page End: 362
• Publication Date: 2015-06
• Subjects: Alternative medicine -- Periodicals; Complementary Therapies -- Periodicals; Médecines parallèles -- Périodiques; Thérapeutique -- Périodiques; Alternative medicine; Electronic journals; Periodicals; 615.5
• DOI: 10.1016/j.ctim.2015.03.008
• Languages: English
• ISSNs: 0965-2299

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Probiotics reduced grade 3–4 diarrhea after irinotecan based chemotherapy.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Probiotics reduced all grades of diarrhea and enterocolitis compared to placebo.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Patients on probiotics used less antidiarrheal drugs compared to placebo.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">Probiotics could reduce gastrointestinal toxicity of irinotecan based therapy.</p> </list-item> </list> </p> </sec> </abstract>