NUP98/11p15 translocations affect CD34+ cells in myeloid and T lymphoid leukemias. Issue 7 (July 2015)

• Record Type: Journal Article
• Authors: Crescenzi, Barbara; Nofrini, Valeria; Barba, Gianluca; Matteucci, Caterina; Di Giacomo, Danika; Gorello, Paolo; Beverloo, Berna; Vitale, Antonella; Wlodarska, Iwona; Vandenberghe, Peter; La Starza, Roberta; Mecucci, Cristina
• Is Part Of: Leukemia research. Volume 39:Issue 7(2015:Jul.)
• Page Start: 769
• Page End: 772
• Publication Date: 2015-07
• Subjects: Leukemia -- Periodicals; Leukemia -- Periodicals; Leucémie -- Périodiques; Leukemia; Periodicals; Electronic journals; Electronic journals; 616.9941905
• DOI: 10.1016/j.leukres.2015.04.014
• Languages: English
• ISSNs: 0145-2126

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005"> <italic>NUP98</italic> translocations are early leukemic lesions which affect a CD34+/CD133+ precursor.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">The NUP98/RAP1GDS1 fusion affected different lineages in AML and T-ALL.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">MDS/AML and T-ALL showed additional myeloid and T cell-lineage specific mutations, respectively.</p> </list-item> </list> </p> </sec> </abstract>