A new group of anti-lipopolysaccharide factors from Marsupenaeus japonicus functions in antibacterial response. Issue 1 (January 2015)

• Record Type: Journal Article
• Authors: Jiang, Hai-Shan; Zhang, Qing; Zhao, Yan-Ran; Jia, Wen-Ming; Zhao, Xiao-Fan; Wang, Jin-Xing
• Is Part Of: Developmental and comparative immunology. Volume 48:Issue 1(2015)
• Page Start: 33
• Page End: 42
• Publication Date: 2015-01
• Subjects: Immunology -- Periodicals; Developmental immunology -- Periodicals; 616.079
• DOI: 10.1016/j.dci.2014.09.001
• Languages: English
• ISSNs: 0145-305X

Abstract

<abstract abstract-type="author-highlights" id="ab0010"> <title id="st0010">Highlights</title> <sec> <p id="sp0010"> <list id="ulist0010"> <list-item id="u0010"> <label></label> <p id="p0010">A new group of ALFs (MjALF-E1 and E2) was identified in <italic>Marsupenaeus japonicus</italic>.</p> </list-item> <list-item id="u0015"> <label></label> <p id="p0015">Both <italic>Mj</italic>ALF-E1 and E2 were upregulated by G⁺ and G⁻ bacterial challenge.</p> </list-item> <list-item id="u0020"> <label></label> <p id="p0020"> <italic>Mj</italic>ALF-E1 and E2 strongly bind to bacterial cell wall components LPS and PGN.</p> </list-item> <list-item id="u0025"> <label></label> <p id="p0025"> <italic>Mj</italic>ALF-E2 exhibited antimicrobial activity against Gram-negative bacteria.</p> </list-item> <list-item id="u0030"> <label></label> <p id="p0030"> <italic>Mj</italic>ALF-E2 promotes the clearance of bacteria in shrimp.</p> </list-item> </list> </p> </sec> </abstract>