Amphioxus as a model for investigating evolution of the vertebrate immune system. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Yuan, Shaochun; Ruan, Jie; Huang, Shengfeng; Chen, Shangwu; Xu, Anlong
• Is Part Of: Developmental and comparative immunology. Volume 48:Issue 2(2015)
• Page Start: 297
• Page End: 305
• Publication Date: 2015-02
• Subjects: Immunology -- Periodicals; Developmental immunology -- Periodicals; 616.079
• DOI: 10.1016/j.dci.2014.05.004
• Languages: English
• ISSNs: 0145-305X

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st055">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0125">The digestive system is the major defense line of cephalochordate amphioxus.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0130">Amphioxus has lymphocyte-likes cells, macrophage-like cells and monocyte-like cells.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0135">Amphioxus has some basic components of vertebrate adaptive immunity (VAI).</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0140">Amphioxus has an extraordinarily complex innate immunity, created by huge expansions of many innate gene families.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0145">Amphioxus has unique features to become an important model for understanding the phylogeny of immunity.</p> </list-item> </list> </p> </sec> </abstract>