Comparison of the metabolic activation of environmental carcinogens in mouse embryonic stem cells and mouse embryonic fibroblasts. Issue 1 (February 2015) - Krais, Annette M.
Highlights ES cells and MEF have the metabolic competence to activate environmental carcinogens. Carcinogen-induced genotoxicity in MEFs is higher than in ES cells. MEFs have higher metabolic capacity than ES cells. Metabolic capacity depends on the carcinogen studied.