Adaptation of a dynamic in vitro model with real-time determination of butyrylcholinesterase activity in the presence of cyclosarin and an oxime. Issue 1 (February 2015)

• Record Type: Journal Article
• Authors: Worek, Franz; Horn, Gabriele; Wille, Timo; Thiermann, Horst
• Is Part Of: Toxicology in vitro. Volume 29:Issue 1(2015)
• Page Start: 162
• Page End: 167
• Publication Date: 2015-02
• Subjects: Toxicity testing -- In vitro -- Periodicals; Toxicology -- Periodicals; 615.9
• DOI: 10.1016/j.tiv.2014.10.003
• Languages: English
• ISSNs: 0887-2333

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st070">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0140">We adopted an in vitro model for the continuous real-time determination of human BChE activity.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0145">The interactions of human BChE, cyclosarin and the oxime HLö 7 were investigated.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0150">This model allows the investigation of BChE as a 'pseudo-catalytic' scavenger.</p> </list-item> </list> </p> </sec> </abstract>