Effects of monocrotophos pesticide on steroidogenesis and transcription of steroidogenic enzymes in rainbow trout RTG-2 cells involving the protein kinase A signal pathway. Issue 1 (February 2015)

• Record Type: Journal Article
• Authors: Wang, Zhenyu; Zhang, Xiaona; Tian, Hua; Wang, Wei; Ru, Shaoguo
• Is Part Of: Toxicology in vitro. Volume 29:Issue 1(2015)
• Page Start: 155
• Page End: 161
• Publication Date: 2015-02
• Subjects: Toxicity testing -- In vitro -- Periodicals; Toxicology -- Periodicals; 615.9
• DOI: 10.1016/j.tiv.2014.10.001
• Languages: English
• ISSNs: 0887-2333

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st085">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0160">MCP promoted the expression of steroidogenic enzymes in rainbow trout cells.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0165">MCP dysregulated the production of steroid hormones 17<italic>β</italic>-estradiol and testosterone.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0170">MCP disrupted the biosynthesis of sex hormones via the PKA signaling pathway.</p> </list-item> </list> </p> </sec> </abstract>