Systematic evaluation of non-animal test methods for skin sensitisation safety assessment. Issue 1 (February 2015)

• Record Type: Journal Article
• Authors: Reisinger, Kerstin; Hoffmann, Sebastian; Alépée, Nathalie; Ashikaga, Takao; Barroso, Joao; Elcombe, Cliff; Gellatly, Nicola; Galbiati, Valentina; Gibbs, Susan; Groux, Hervé; Hibatallah, Jalila; Keller, Donald; Kern, Petra; Klaric, Martina; Kolle, Susanne; Kuehnl, Jochen; Lambrechts, Nathalie; Lindstedt, Malin; Millet, Marion; Martinozzi-Teissier, Silvia; Natsch, Andreas; Petersohn, Dirk; Pike, Ian; Sakaguchi, Hitoshi; Schepky, Andreas; Tailhardat, Magalie; Templier, Marie; van Vliet, Erwin; Maxwell, Gavin
• Is Part Of: Toxicology in vitro. Volume 29:Issue 1(2015)
• Page Start: 259
• Page End: 270
• Publication Date: 2015-02
• Subjects: Toxicity testing -- In vitro -- Periodicals; Toxicology -- Periodicals; 615.9
• DOI: 10.1016/j.tiv.2014.10.018
• Languages: English
• ISSNs: 0887-2333

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab010"> <title id="st210">Highlights</title> <sec> <p id="sp0045"> <list id="l0010"> <list-item id="o0035"> <label></label> <p id="p0295">Non-animal data for skin sensitisation risk assessment are urgently needed.</p> </list-item> <list-item id="o0040"> <label></label> <p id="p0300">This has led to the development of a number of <italic>in vitro</italic> test methods.</p> </list-item> <list-item id="o0045"> <label></label> <p id="p0305">Cosmetics Europe (CE) systematically evaluated 16 of these methods.</p> </list-item> <list-item id="o0050"> <label></label> <p id="p0310">Methods were prioritised for further in-depth evaluation.</p> </list-item> <list-item id="o0055"> <label></label> <p id="p0315">CE will develop a testing strategy for skin sensitiser potency prediction.</p> </list-item> </list> </p> </sec> </abstract>