Comparative study on thiol drugs' effect on tert-butyl hydroperoxide induced luminol chemiluminescence in human erythrocyte lysate and hemoglobin oxidation. Issue 1 (February 2015)

• Record Type: Journal Article
• Authors: Sajewicz, Waldemar; Zalewska, Marta; Milnerowicz, Halina
• Is Part Of: Toxicology in vitro. Volume 29:Issue 1(2015)
• Page Start: 148
• Page End: 154
• Publication Date: 2015-02
• Subjects: Toxicity testing -- In vitro -- Periodicals; Toxicology -- Periodicals; 615.9
• DOI: 10.1016/j.tiv.2014.09.001
• Languages: English
• ISSNs: 0887-2333

Abstract

<abstract xml:lang="en" abstract-type="author-highlights" id="ab005"> <title id="st080">Highlights</title> <sec> <p id="sp0005"> <list id="l0005"> <list-item id="o0005"> <label></label> <p id="p0170">Three types of chemiluminescence kinetic under influence of thiol drugs.</p> </list-item> <list-item id="o0010"> <label></label> <p id="p0175">Various proportion of methemoglobin/hemichromes formation under influence of thiols.</p> </list-item> <list-item id="o0015"> <label></label> <p id="p0180">Thiol-derived secondary free radicals can be accelerated by the modification of globin.</p> </list-item> <list-item id="o0020"> <label></label> <p id="p0185">Heterogeneity of reaction mechanisms depends on structural relationship of thiol drugs.</p> </list-item> <list-item id="o0025"> <label></label> <p id="p0190">Thiol drugs can create danger of propagation and amplification of oxidative stress.</p> </list-item> </list> </p> </sec> </abstract>