IgE recognition of chimeric isoforms of the honeybee (Apis mellifera) venom allergen Api m 10 evaluated by protein array technology. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Van Vaerenbergh, Matthias; De Smet, Lina; Rafei-Shamsabadi, David; Blank, Simon; Spillner, Edzard; Ebo, Didier G.; Devreese, Bart; Jakob, Thilo; de Graaf, Dirk C.
• Is Part Of: Molecular immunology. Volume 63:Issue 2(2015:Feb.)
• Page Start: 449
• Page End: 455
• Publication Date: 2015-02
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2014.09.018
• Languages: English
• ISSNs: 0161-5890

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Nine additional Api m 10 transcript isoforms are discovered.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">The previously known variant 2 is produced by an alternative splicing event.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Novel identified isoforms are intragenic chimeric transcripts.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">IgE recognition of Api m 10 is both isoform- and patient-specific.</p> </list-item> </list> </p> </sec> </abstract>