Maintaining dendritic cell viability in culture. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Vremec, David; Hansen, Jacinta; Strasser, Andreas; Acha-Orbea, Hans; Zhan, Yifan; O'Keeffe, Meredith; Shortman, Ken
• Is Part Of: Molecular immunology. Volume 63:Issue 2(2015:Feb.)
• Page Start: 264
• Page End: 267
• Publication Date: 2015-02
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2014.07.011
• Languages: English
• ISSNs: 0161-5890

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Mouse DCs die even more rapidly in culture than <italic>in vivo</italic>.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">GM-CSF conserves the culture viability of conventional DCs, but not of plasmacytoid DC.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Plasmacytoid DCs from mice overexpressing Bcl-2 have prolonged survival in culture.</p> </list-item> </list> </p> </sec> </abstract>