Autoantibodies to CD59, CD55, CD46 or CD35 are not associated with atypical haemolytic uraemic syndrome (aHUS). Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Watson, Rachael; Wearmouth, Emma; McLoughlin, Amy-Claire; Jackson, Arthur; Ward, Sophie; Bertram, Paula; Bennaceur, Karim; Barker, Catriona E.; Pappworth, Isabel Y.; Kavanagh, David; Lea, Susan M.; Atkinson, John P.; Goodship, Timothy H.J.; Marchbank, Kevin J.
• Is Part Of: Molecular immunology. Volume 63:Issue 2(2015:Feb.)
• Page Start: 287
• Page End: 296
• Publication Date: 2015-02
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2014.07.017
• Languages: English
• ISSNs: 0161-5890

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0065"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">First report of analysis of aHUS patients for autoantibodies to CD46, CD55, CD35 and CD59.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Surprisingly no aAb to surface bound complement regulators found in association with aHUS.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Surface regulators could be protected from mechanisms of autoantibody formation in aHUS.</p> </list-item> </list> </p> </sec> </abstract>