Porphyromonas gingivalis HSP60 peptides have distinct roles in the development of atherosclerosis. Issue 2 (February 2015)

• Record Type: Journal Article
• Authors: Jeong, Euikyong; Kim, Koanhoi; Kim, June Hong; Cha, Gil Sun; Kim, Sung-Jo; Kang, Ho Sung; Choi, Jeomil
• Is Part Of: Molecular immunology. Volume 63:Issue 2(2015:Feb.)
• Page Start: 489
• Page End: 496
• Publication Date: 2015-02
• Subjects: Immunochemistry -- Periodicals; Molecular biology -- Periodicals; Immunochemistry -- Periodicals; Allergy and Immunology -- Periodicals; Molecular Biology -- Periodicals; Immunochimie -- Périodiques; Biologie moléculaire -- Périodiques; Immunochemistry; Molecular biology; Periodicals; Electronic journals; 571.96
• DOI: 10.1016/j.molimm.2014.10.004
• Languages: English
• ISSNs: 0161-5890

Abstract

<abstract abstract-type="author-highlights" id="abs0005"> <title id="sect0005">Highlights</title> <sec> <p id="spar0005"> <list id="lis0005"> <list-item id="lsti0005"> <label></label> <p id="par0005">Epitope Pg14 is anti-atherogenic and Pg19 is proatherogenic in ApoE KO mice.</p> </list-item> <list-item id="lsti0010"> <label></label> <p id="par0010">Pg14 induces regulatory T cells while Pg19 stimulates Th1 cells.</p> </list-item> <list-item id="lsti0015"> <label></label> <p id="par0015">Transcriptional factors Nr4a1 and Nr4a2 are up-regulated by Pg14, but not by Pg19.</p> </list-item> <list-item id="lsti0020"> <label></label> <p id="par0020">BMDC drives regulatory T cells in antigen-nonspecific manner.</p> </list-item> </list> </p> </sec> </abstract>