Effect of silver diamine fluoride and potassium iodide on residual bacteria in dentinal tubules. (March 2015)

• Record Type: Journal Article
• Authors: Hamama, HH; Yiu, CK; Burrow, MF
• Is Part Of: Australian dental journal. Volume 60:Number 1(2015:Mar.)
• Page Start: 80
• Page End: 87
• Publication Date: 2015-03
• Subjects: Dentistry -- Periodicals; Dentistry -- Periodicals; Dentisterie -- Australie -- Périodiques; Tandheelkunde; 617.6
• DOI: 10.1111/adj.12276
• Languages: English
• ISSNs: 0045-0421

Abstract

<abstract abstract-type="main" id="adj12276-abs-0001"> <title>Abstract</title> <sec id="adj12276-sec-0001" sec-type="section"> <title>Background</title> <p>This study evaluated the antimicrobial effect of a silver diamine fluoride (SDF)/potassium iodide (KI) product (Riva Star) on the viability of intratubular bacteria.</p> </sec> <sec id="adj12276-sec-0002" sec-type="section"> <title>Methods</title> <p>Forty‐five dentine discs prepared from caries‐free maxillary premolars were randomly divided into nine groups. Group 1 (negative control) contained non‐infected sound dentine discs. The remaining discs were infected with <italic>Streptococcus mutans</italic> suspension and received dentine treatments as follows: Group 2 (positive control), discs were left untreated; Group 3 SDF/KI (Riva Star); Group 4 chlorhexidine (CHX); Group 5 CHX + SDF/KI; Group 6 Carisolv; Group 7 Carisolv + SDF/KI; Group 8 Papacarie, and Group 9 Papacarie + SDF/KI. The discs were then fractured into two halves, stained with fluorescent LIVE/DEAD stain and observed using confocal laser scanning microscopy.</p> </sec> <sec id="adj12276-sec-0003" sec-type="section"> <title>Results</title> <p>SDF/KI exhibited a potent antibacterial effect, as represented by a significantly higher percentage of dead bacteria, in comparison with Carisolv and Papacarie (p < 0.05). The application of SDF/KI following Carisolv and Papacarie chemomechanical caries removel gels significantly reduced the viability of intra‐tubular bacteria in these groups.</p> </sec> <sec id="adj12276-sec-0004" sec-type="section"> <title>Conclusions</title> <p>The use of the silver diamine fluoride/potassium iodide product is effective in reducing the numbers of <italic>S. mutans</italic> in dentinal tubules infected with this organism.</p> </sec> </abstract>