Influence of Pseudophakic Lens Capsule Opacification on Spectral Domain and Time Domain Optical Coherence Tomography Image Quality. (May 2015)

• Record Type: Journal Article
• Authors: Cagini, Carlo; Pietrolucci, Francesca; Lupidi, Marco; Messina, Marco; Piccinelli, Francesco; Fiore, Tito
• Is Part Of: Current eye research. Volume 40:Number 6(2015:Jun.)
• Page Start: 579
• Page End: 584
• Publication Date: 2015-05
• Subjects: Ophthalmology -- Periodicals; Eye -- Diseases -- Periodicals; Ophthalmology -- Periodicals; 573.88
• DOI: 10.3109/02713683.2014.941069
• Languages: English
• ISSNs: 0271-3683

Abstract

<abstract> <title>Abstract</title> <p> <italic>Purpose</italic>: To evaluate the influence of posterior capsule opacification (PCO) on optical coherence tomography (OCT) acquisition of macular retinal thickness (RT) and volume using time domain OCT (TD-OCT) and spectral domain OCT (SD-OCT).</p> <p> <italic>Materials and methods</italic>: We studied 37 eyes of 31 patients with PCO. Each patient underwent an evaluation with TD-OCT and with SD-OCT before and after Nd:YAG capsulotomy. We recorded RT and retinal volume in the macular area using only good quality images.</p> <p> <italic>Results</italic>: Best corrected visual acuity improved in all eyes after Nd:YAG capsulotomy, with the degree of improvement ranging from 0.3 ±<underline> </underline>0.7 to 0.1 ±0.7 (<italic>p </italic>= 0.01). Before the treatment, only 27% of the examinations were valuable with TD-OCT, while using SD-OCT, it was possible to obtain an examination of suitable quality both before and after the Yag laser capsulotomy in 100% of the eyes. We did not observe significant differences between mean preoperative and postoperative RT and total macular volume measurements, neither with TD-OCT nor with SD-OCT. RT and total macular volume values obtained using TD-OCT were always lower than those obtained from the SD-OCT, both before and after capsulotomy.</p> <p> <italic>Conclusions</italic>: Our study confirmed that with old generation TD-OCT, PCO has a strong negative influence on the quality of OCT acquisition, and examination is reliable only when it is possible to acquire good quality images. With new generation SD-OCT, tomographic acquisitions are always reliable and are not influenced by the presence of PCO.</p> </abstract>