Impact of single and multiple sets of resistance exercise in type 1 diabetes. Issue 1 (20th March 2014)

• Record Type: Journal Article
• Authors: Turner, D.; Luzio, S.; Gray, B. J.; Dunseath, G.; Rees, E. D.; Kilduff, L. P.; Campbell, M. D.; West, D. J.; Bain, S. C.; Bracken, R. M.
• Is Part Of: Scandinavian journal of medicine & science in sports. Volume 25:Issue 1(2015)
• Page Start: e99
• Page End: e109
• Publication Date: 2014-03-20
• Subjects: Sports medicine -- Periodicals; Sports -- Physiological aspects -- Periodicals; Sports -- Periodicals; 617.1027
• DOI: 10.1111/sms.12202
• Languages: English
• ISSNs: 0905-7188

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>To examine glycemic and glucoregulatory responses to resistance exercise (RE) sessions of different volume in type 1 diabetes (T1DM). Eight T1DM (seven males: one female; age: 38 ± 6 years, HbA<sub>1C</sub>: 8.7 ± 1.0%/71 ± 11 mmol/mol) attended the research facility fasted and on four separate occasions, having taken their usual basal insulin, but omitted morning rapid‐acting insulin. Participants completed a 1SET (14 min), 2SET (28 min), 3SET (42 min) RE session (eight exercises × 10 repetitions) at 67 ± 3% one‐repetition‐maximum followed by 60‐min recovery, or a resting trial (CON). Venous blood samples were taken before and after exercise. Data (mean ± SEM) were analyzed using repeated‐measures analysis of variance (<italic>P</italic> ≤ 0.05). RE did not induce hypoglycemia (BG < 4 mmol/L). During recovery, blood glucose (BG) concentrations remained above pre‐exercise after 1SET (15–60 min, <italic>P</italic> < 0.05) and 2SET (0–60 min, <italic>P</italic> < 0.05) but comparable (<italic>P</italic> > 0.05) with pre‐exercise after 3SET. BG<sub>IAUC(area‐under‐curve)</sub> (mmol/L/60 min) was greater after 1SET and 2SET vs CON (1SET 103.6 ± 36.9 and 2SET 128.7 ± 26.1 vs CON −24.3 ± 15.2, <italic>P</italic> < 0.05), but similar between 3SET and CON (3SET 40.7 ± 59.3, <italic>P</italic> > 0.05). Under all trials, plasma creatine kinase levels at 24 h post‐exercise were similar (<italic>P</italic> > 0.05) to pre‐exercise. RE does not induce acute hypoglycemia or damage muscle. BG progressively rose after one and two sets of RE. However, inclusion of a third set attenuated exercise‐induced hyperglycemia and returned BG to that of a non‐exercise trial.</p> </abstract>