The spectrum of clinical presentation, diagnosis, and management of mitochondrial forms of diabetes. Issue 1 (20th October 2014)

• Record Type: Journal Article
• Authors: Karaa, Amel; Goldstein, Amy
• Is Part Of: Pediatric diabetes. Volume 16:Issue 1(2015:Feb.)
• Page Start: 1
• Page End: 9
• Publication Date: 2014-10-20
• Subjects: Diabetes in children -- Periodicals; 616.462
• DOI: 10.1111/pedi.12223
• Languages: English
• ISSNs: 1399-543X

Abstract

<abstract abstract-type="main" id="pedi12223-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p id="pedi12223-para-0001">Primary mitochondrial diseases refer to a group of heterogeneous and complex genetic disorders affecting 1:5000 people. The true prevalence is anticipated to be even higher because of the complexity of achieving a diagnosis in many patients who present with multisystemic complaints ranging from infancy to adulthood. Diabetes is a prominent feature of several of these disorders which might be overlooked by the endocrinologist. We here review mitochondrial disorders and describe the phenotypic and pathogenetic differences between mitochondrial diabetes mellitus (mDM) and other more common forms of diabetes mellitus.</p> </abstract>