Breast milk leptin and adiponectin in relation to infant body composition up to 2 years. Issue 1 (14th April 2014)

• Record Type: Journal Article
• Authors: Brunner, S.; Schmid, D.; Zang, K.; Much, D.; Knoeferl, B.; Kratzsch, J.; Amann‐Gassner, U.; Bader, B. L.; Hauner, H.
• Is Part Of: Pediatric obesity. Volume 10:Issue 1(2015:Feb.)
• Page Start: 67
• Page End: 73
• Publication Date: 2014-04-14
• Subjects: Obesity in children -- Periodicals; Obesity in adolescence -- Periodicals; Obesity -- Periodicals; Overweight children -- Periodicals; 618.92398
• DOI: 10.1111/j.2047-6310.2014.222.x
• Languages: English
• ISSNs: 1747-7174

Abstract

<abstract abstract-type="main"> <title>Summary</title> <sec id="ijpo222-sec-0003" sec-type="section"> <title>Background</title> <p>Adipokines in breast milk have been associated with infant growth trajectories.</p> </sec> <sec id="ijpo222-sec-0004" sec-type="section"> <title>Objective</title> <p>We aimed to explore the relationship of leptin and adiponectin in breast milk with infant weight gain and body composition up to the age of 2 years.</p> </sec> <sec id="ijpo222-sec-0005" sec-type="section"> <title>Methods</title> <p>Breast milk samples were collected from exclusively or partially breastfeeding mothers at 6 weeks (<italic>n</italic> = 152) and 4 months (<italic>n</italic> = 120) post‐partum. Leptin and adiponectin were determined in skim breast milk and related to infant growth and fat mass assessed by skin‐fold thickness measurements. A total of 118 infants were examined at 2 years.</p> </sec> <sec id="ijpo222-sec-0006" sec-type="section"> <title>Results</title> <p>The levels of both milk adipokines were slightly lower at 4 months compared with 6 weeks post‐partum. Breast milk leptin was largely unrelated to infant anthropometric measures up to 2 years. Milk adiponectin tended to be inversely related to early infant anthropometry up to 4 months, but beyond was positively associated with weight gain and the sum of skin‐folds up to 2 years.</p> </sec> <sec id="ijpo222-sec-0007" sec-type="section"> <title>Conclusions</title> <p>Our results suggest that higher adiponectin levels in breast milk might be associated with greater weight gain and higher fat mass in the offspring up to 2 years.</p> </sec> </abstract>