Treatment of pseudoepitheliomatous, keratotic, and micaceous balanitis with topical photodynamic therapy. (30th September 2014)

• Record Type: Journal Article
• Authors: Zhu, Hui; Jiang, Yong; Watts, Matthew; Kong, Fanrong
• Is Part Of: International journal of dermatology. Volume 54:Number 2(2015:Feb.)
• Page Start: 245
• Page End: 247
• Publication Date: 2014-09-30
• Subjects: Dermatology -- Periodicals; 616.5
• DOI: 10.1111/ijd.12509
• Languages: English
• ISSNs: 0011-9059

Abstract

<abstract abstract-type="main" id="ijd12509-abs-0001"> <title>Abstract</title> <sec id="ijd12509-sec-0001" sec-type="section"> <title>Background</title> <p>Pseudoepitheliomatous, keratotic, and micaceous balanitis (PKMB) is an extremely rare condition occurring over the glans in older men who undergo circumcision late in life. Its exact etiology is unknown.</p> </sec> <sec id="ijd12509-sec-0002" sec-type="section"> <title>Objectives</title> <p>We report a patient with PKMB that involved the meatus and led to urinary obstruction.</p> </sec> <sec id="ijd12509-sec-0003" sec-type="section"> <title>Methods</title> <p>A 57‐year‐old, circumcised man presented with partial urinary obstruction caused by a thick, nail‐like covering on the skin of his glans penis. Based on histology, PKMB was diagnosed. There was no cytological atypia. The patient was treated successfully with topical 5‐aminolevulinic acid (ALA) photodynamic therapy (PDT).</p> </sec> <sec id="ijd12509-sec-0004" sec-type="section"> <title>Results</title> <p>There was no recurrence after 18 months of follow‐up. Treatment with ALA–PDT seems to be effective and well tolerated in PKMB.</p> </sec> <sec id="ijd12509-sec-0005" sec-type="section"> <title>Conclusions</title> <p>This case indicates that ALA–PDT may be an effective treatment option for plaque‐stage PKMB and thus warrants further investigation.</p> </sec> </abstract>