An efficient, mild and selective Ullmann‐type N‐arylation of indoles catalysed by Pd immobilized on amidoxime‐functionalized mesoporous SBA‐15 as heterogeneous and recyclable nanocatalyst. (3rd February 2015)

• Record Type: Journal Article
• Authors: Ghorbani‐Vaghei, Ramin; Hemmati, Saba; Hamelian, Mona; Veisi, Hojat
• Is Part Of: Applied organometallic chemistry. Volume 29:Number 4(2015:Apr.)
• Page Start: 195
• Page End: 199
• Publication Date: 2015-02-03
• Subjects: Organometallic chemistry -- Periodicals; Organometallic compounds -- Periodicals; 547.05
• DOI: 10.1002/aoc.3264
• Languages: English
• ISSNs: 0268-2605

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>A wide range of <italic>N</italic>‐arylated indoles were selectively synthesized through <named-content content-type="reactionType" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">intermolecular</named-content> C(aryl)N bond formation from the corresponding aryl iodides and indoles through Ullmann‐type <named-content content-type="reactionType" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">coupling reactions</named-content> in the presence of a catalytic amount of Pd immobilized on amidoxime‐functionalized mesoporous SBA‐15 (SBA‐15/AO/Pd(0)) under mild reaction conditions. These cross‐coupled products were obtained in excellent yields under mild conditions at extremely low palladium loading (<italic>ca</italic> 0.3 mol%), and the heterogeneous catalyst can be readily recovered by simple filtration and reused seven times with loss in its activity. Copyright © 2015 John Wiley &amp; Sons, Ltd.</p> </abstract>