A delocalizable cationic headgroup together with an oligo-oxyethylene spacer in gemini cationic lipids improves their biological activity as vectors of plasmid DNA1. Issue 8 (28th February 2015)

• Record Type: Journal Article
• Authors: Kumar, Krishan; Barrán-Berdón, Ana L.; Datta, Sougata; Muñoz-Úbeda, Mónica; Aicart-Ramos, Clara; Kondaiah, Paturu; Junquera, Elena; Bhattacharya, Santanu; Aicart, Emilio
• Is Part Of: Journal of materials chemistry. Volume 3:Issue 8(2015)
• Page Start: 1495
• Page End: 1506
• Publication Date: 2015-02-28
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c4tb01948b
• Languages: English
• ISSNs: 2050-750X

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj412xcdt" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Lipoplexes of plasmid DNA and mixed liposomes, with a gemini cationic lipid of the 1, 2-bis(hexadecyl imidazolium) oxyethylene series, improves their biological activity.</p> </abstract>