Semi-synthesis of a HGF/SF kringle one (K1) domain scaffold generates a potent in vivo MET receptor agonist1. Issue 3 (16th March 2015)

• Record Type: Journal Article
• Authors: Simonneau, Claire; Bérénice Leclercq; Mougel, Alexandra; Adriaenssens, Eric; Paquet, Charlotte; Raibaut, Laurent; Ollivier, Nathalie; Drobecq, Hervé; Marcoux, Julien; Cianférani, Sarah; Tulasne, David; de Jonge, Hugo; Melnyk, Oleg; Vicogne, Jérôme
• Is Part Of: Chemical science. Volume 6:Issue 3(2015:Mar.)
• Page Start: 2110
• Page End: 2121
• Publication Date: 2015-03-16
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c4sc03856h
• Languages: English
• ISSNs: 2041-6520

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj412csrm" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Clustering of synthetic biotinylated K1 domain from HGF/SF by streptavidin is sufficient to generate a potent MET agonist.</p> </abstract>