Acylation or phosphorylation of hydroxyurea unexpectedly takes place on N rather than on O, leading to the formation of amides instead of the expected esters1. Issue 31 (8th April 2015)

Record Type:: Journal Article
Title:: Acylation or phosphorylation of hydroxyurea unexpectedly takes place on N rather than on O, leading to the formation of amides instead of the expected esters1. Issue 31 (8th April 2015)
Main Title:: Acylation or phosphorylation of hydroxyurea unexpectedly takes place on N rather than on O, leading to the formation of amides instead of the expected esters1
Authors:: Pariente-Cohen, Natalie
Weitman, Michal
Tania, Nassdyuk
Major, Dan T.
Gottlieb, Hugo E.
Hoz, Shmaryahu
Nudelman, Abraham
Abstract:: <abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjbg0mmv2" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />Attempted acylation of the anticancer agent hydroxyurea (HU) with acyl chlorides or anhydrides led to acylation on the NH group rather than on the OH.</p> </abstract>
Is Part Of:: RSC advances. Volume 5:Issue 31(2015)
Journal:: RSC advances
Issue:: Volume 5:Issue 31(2015)
Issue Display:: Volume 5, Issue 31 (2015)
Year:: 2015
Volume:: 5
Issue:: 31
Issue Sort Value:: 2015-0005-0031-0000
Page Start:: 24038
Page End:: 24043
Publication Date:: 2015-04-08
Subjects:: Chemistry -- Periodicals
540.5
Journal URLs:: http://pubs.rsc.org/en/Journals/JournalIssues/RA ↗
http://www.rsc.org/ ↗
DOI:: 10.1039/c5ra01016k ↗
Languages:: English
ISSNs:: 2046-2069
Deposit Type:: Legaldeposit
View Content:: Available online (eLD content is only available in our Reading Rooms) ↗
Physical Locations:: British Library DSC - 8036.750300
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store
Ingest File:: 3542.xml