Vesicular disruption of lysosomal targeting organometallic polyarginine bioconjugates1. Issue 2 (11th March 2015) - Gross, Annika
Abstract Targeting of lysosomes is an interesting, novel pathway for cancer therapy. in this work, novel metallocene derivatives (of ferrocene and ruthenocene) of a cell penetrating polyarginine peptide are presented as lysosomal membrane permeabilization (LMP) agents and their localization and biological activity is investigated in detail.