A set of robust fluorescent peptide probes for quantification of Cu(ii) binding affinities in the micromolar to femtomolar range1. Issue 3 (11th March 2015)

• Record Type: Journal Article
• Authors: Young, Tessa R.; Wijekoon, Chathuri J. K.; Spyrou, Benjamin; Donnelly, Paul S.; Wedd, Anthony G.; Xiao, Zhiguang
• Is Part Of: Metallomics. Volume 7:Issue 3(2015:Mar.)
• Page Start: 567
• Page End: 578
• Publication Date: 2015-03-11
• Subjects: Metals -- Physiological effect -- Periodicals; 572.51
• DOI: 10.1039/c4mt00301b
• Languages: English
• ISSNs: 1756-5901

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgjbfw6j7s" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />A set of four fluorescent probes were developed and demonstrated to be capable of quantifying Cu(<sc>ii</sc>) binding affinities in the micromolar to femtomolar range and exploring Cu(<sc>ii</sc>) binding ligands in peptides and proteins.</p> </abstract>