A metal-based tumour necrosis factor-alpha converting enzyme inhibitor1. Issue 19 (7th March 2015)

• Record Type: Journal Article
• Authors: Leung, Chung-Hang; Liu, Li-Juan; Lu, Lihua; He, Bingyong; Kwong, Daniel W. J.; Wong, Chun-Yuen; Ma, Dik-Lung
• Is Part Of: Chemical communications. Volume 51:Issue 19(2015)
• Page Start: 3973
• Page End: 3976
• Publication Date: 2015-03-07
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c4cc09251a
• Languages: English
• ISSNs: 1359-7345

Abstract

<abstract abstract-type="toc"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <graphic position="anchor" id="ga" xlink:href="ark:/27927/pgj40v1nj7" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" />We report herein a novel iridium(<sc>iii</sc>) complex <bold>1</bold> as an antitumour necrosis factor agent and the first metal-based inhibitor of TACE enzymatic activity.</p> </abstract>