Survival of AIDS‐related diffuse large B‐cell lymphoma, Burkitt lymphoma, and plasmablastic lymphoma in the German HIV Lymphoma Cohort. (17th November 2014)

• Record Type: Journal Article
• Authors: Schommers, Philipp; Hentrich, Marcus; Hoffmann, Christian; Gillor, Daniel; Zoufaly, Alexander; Jensen, Björn; Bogner, Johannes R.; Thoden, Jan; Wasmuth, Jan‐Christian; Wolf, Timo; Oette, Mark; Müller, Markus; Esser, Stefan; Vehreschild, Jörg J.; Fätkenheuer, Gerd; Wyen, Christoph
• Is Part Of: British journal of haematology. Volume 168:Number 6(2015:Mar.)
• Page Start: 806
• Page End: 810
• Publication Date: 2014-11-17
• Subjects: Hematology -- Periodicals; Blood -- Diseases -- Periodicals; 616.15
• DOI: 10.1111/bjh.13221
• Languages: English
• ISSNs: 0007-1048

Abstract

<abstract abstract-type="main" id="bjh13221-abs-0001"> <title>Summary</title> <p>Overall survival (OS) of patients with acquired immunodeficiency syndrome (AIDS)‐related Burkitt lymphoma (BL), diffuse large B‐cell lymphoma (DLBCL) and plasmablastic lymphoma (PBL) was analysed in the German AIDS‐related‐Lymphoma‐Cohort‐Study. Of 291 patients prospectively included between January 2005 and December 2012, 154 had DLBCL, 103 BL and 34 PBL. Two‐year OS rates were similar between BL (69%) and DLBCL patients (63%) but lower for PBL patients (43%). Intermediate (Hazard ratio [HR] 4·1 95% confidence interval [CI] 1·98–8·49) or high (HR 4·92 95% CI 2·1–11·61) International Prognostic Index, bone marrow involvement (HR 1·69 95% CI 1·00–2·84) and PBL histology (HR 2·24 95% CI 1·24–4·03) were independent predictors of mortality.</p> </abstract>