Neonatal acute megakaryoblastic leukemia mimicking congenital neuroblastoma. Issue 3 (2nd December 2014)

• Record Type: Journal Article
• Authors: Kawasaki, Yukako; Makimoto, Masami; Nomura, Keiko; Hoshino, Akihiro; Hamashima, Takeru; Hiwatari, Mitsuteru; Nakazawa, Atsuko; Takita, Junko; Yoshida, Taketoshi; Kanegane, Hirokazu
• Is Part Of: Clinical case reports. Volume 3:Issue 3(2015:Jun.)
• Page Start: 145
• Page End: 149
• Publication Date: 2014-12-02
• Subjects: Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.183
• Languages: English
• ISSNs: 2050-0904

Abstract

<abstract abstract-type="main" id="ccr3183-abs-0001"> <title>Key Clinical Message</title> <p>We describe a neonate with abdominal distension, massive hepatomegaly, and high serum neuron‐specific enolase level suggestive of congenital neuroblastoma. The patient died of pulmonary hemorrhage after therapy. Autopsy revealed that the tumor cells in the liver indicated acute megakaryocytic leukemia with the <italic>RBM15‐MKL1</italic> fusion gene.</p> </abstract>