Inhibition of insulin/IGF‐1 receptor signaling protects from mitochondria‐mediated kidney failure. Issue 3 (2nd February 2015) - Ising, Christina
Abstract Podocyte‐specific PHB2 loss results in severe kidney disease that is alleviated by insulin and IGF‐1 receptors deletion or rapamycin treatment, demonstrating not only a causal link between mitochondrial dysfunction and kidney disease but also putative therapeutic avenues.