Intracellular free fatty acid upholds β‐cell glucose competence: The role of peroxisome proliferator‐activated receptor δ and mitochondrial metabolism. Issue 2 (15th July 2014) - Takei, Masahiro
Abstract Tang et al. identified a novel downstream signaling pathway for intracellular FFA in pancreatic beta cells: activation of peroxisome proliferator‐activated receptor δ (PPARδ) followed by enhanced mitochondrial metabolism. This was accomplished by using beta‐cell specific desnutrin/ATGL knockout (desnutrin βKO) mice.