Case series of patients with chronic foot ulcers treated with autologous platelet‐rich plasma. Issue 3 (23rd January 2015)

• Record Type: Journal Article
• Authors: Yotsu, Rie R.; Hagiwara, Shotaro; Okochi, Hitoshi; Tamaki, Takeshi
• Is Part Of: Journal of dermatology. Volume 42:Issue 3(2015)
• Page Start: 288
• Page End: 295
• Publication Date: 2015-01-23
• Subjects: Dermatology -- Periodicals; Dermatology -- Japan -- Periodicals; Skin -- Diseases -- Periodicals; 616.5005
• DOI: 10.1111/1346-8138.12777
• Languages: English
• ISSNs: 0385-2407

Abstract

<abstract abstract-type="main" id="jde12777-abs-0001"> <title>Abstract</title> <p>Treatment for patients with chronic wounds is entering a new era, and autologous platelet‐rich plasma (PRP) is among the most promising treatments. PRP contains a concentration of platelets obtained by centrifuging the patient's blood. Because it contains fibrin and high concentrations of growth factors, PRP is known to promote wound healing. In this study, we present five patients with chronic foot ulcers successfully treated with PRP in our institution. The patients had various underlying diseases: diabetes (<italic>n </italic>= 2), peripheral arterial disease (<italic>n </italic>= 1), both diabetes and peripheral arterial disease (<italic>n </italic>= 1), and cutaneous polyarteritis nodosa (<italic>n </italic>= 1). Also, we provide a description of PRP's mechanisms, advantages, and limitations.</p> </abstract>