Clinical and radiographic outcomes of total hip replacement with poly(2-methacryloyloxyethyl phosphorylcholine)-grafted highly cross-linked polyethylene liners: Three-year results of a prospective consecutive series. Issue 2 (March 2015)

• Record Type: Journal Article
• Authors: Takatori, Yoshio; Moro, Toru; Ishihara, Kazuhiko; Kamogawa, Morihide; Oda, Hiromi; Umeyama, Takashige; Kim, Yoon Taek; Ito, Hideya; Kyomoto, Masayuki; Tanaka, Takeyuki; Kawaguchi, Hiroshi; Tanaka, Sakae
• Is Part Of: Modern rheumatology. Volume 25:Issue 2(2015)
• Page Start: 286
• Page End: 291
• Publication Date: 2015-03
• Subjects: Rheumatology -- Periodicals; 616.723005
• DOI: 10.3109/14397595.2014.941438
• Languages: English
• ISSNs: 1439-7595

Abstract

<abstract> <title>Abstract</title> <p> <italic>Objectives.</italic> This study aimed to evaluate the clinical safety and wear-resistance of the novel highly cross-linked polyethylene (HXLPE) acetabular liner with surface grafting of poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC) at 3 years after total hip replacement (THR).</p> <p> <italic>Methods.</italic> Eighty consecutive patients underwent cementless THR using a 26-mm diameter cobalt–chromium–molybdenum alloy femoral head and a PMPC-grafted HXLPE liner for the bearing couplings. We evaluated the clinical and radiographic outcomes of 76 patients at 3 years after the index surgery.</p> <p> <italic>Results</italic>. The clinical results at 3 years were equivalent to a Harris hip score of 95.6 points. No adverse events were associated with the implanted PMPC-grafted HXLPE liner, and no periprosthetic osteolysis was detected. The mean femoral head penetration rate was 0.002 mm/year, representing marked reduction compared with other HXLPE liners.</p> <p> <italic>Conclusions</italic>. A PMPC-grafted HXLPE liner is a safe option in THR and probably reduces the generation of wear particles.</p> </abstract>