An autopsy case of refractory vasculo-Behçet's disease. Issue 2 (March 2015)

• Record Type: Journal Article
• Authors: Kaieda, Shinjiro; Zaizen, Yoshiaki; Nomura, Yoriko; Okabe, Koki; Honda, Seiyo; Kage, Masayoshi; Ida, Hiroaki; Hoshino, Tomoaki; Fukuda, Takaaki
• Is Part Of: Modern rheumatology. Volume 25:Issue 2(2015)
• Page Start: 307
• Page End: 311
• Publication Date: 2015-03
• Subjects: Rheumatology -- Periodicals; 616.723005
• DOI: 10.3109/14397595.2013.874755
• Languages: English
• ISSNs: 1439-7595

Abstract

<abstract> <title>Abstract</title> <p>Pulmonary vascular involvement in Behçet's disease is a rare complication with a poor prognosis. We present an autopsy case of vasculo-Behçet's disease complicated by pulmonary hemorrhage, possibly caused by rupture of pulmonary artery aneurysms. The patient was treated with a combination of high-dose steroids and pulse cyclophosphamide, but he died from massive hemoptysis. This case highlights the need for potent new therapies for patients with vasculo-Behçet's disease refractory to conventional immunosuppressive therapy, such as a combination of steroids and cyclophosphamide.</p> </abstract>