Brain creatine depletion in vegetarians? A cross-sectional 1H-magnetic resonance spectroscopy (1H-MRS) study. Issue 7 (14th April 2014)

• Record Type: Journal Article
• Authors: Yazigi Solis, Marina; de Salles Painelli, Vítor; Giannini Artioli, Guilherme; Roschel, Hamilton; Concepción Otaduy, Maria; Gualano, Bruno
• Is Part Of: British journal of nutrition. Volume 111:Issue 7(2014)
• Page Start: 1272
• Page End: 1274
• Publication Date: 2014-04-14
• Subjects: Nutrition -- Periodicals; 572.4
• DOI: 10.1017/S0007114513003802
• Languages: English
• ISSNs: 0007-1145

Abstract

<abstract abstract-type="normal"> <title> <x content-type="archive" xml:space="preserve">Abstract</x> </title> <p>The present cross-sectional study aimed to examine the influence of diet on brain creatine (Cr) content by comparing vegetarians with omnivores. Brain Cr content in the posterior cingulate cortex was assessed by proton magnetic resonance spectroscopy (¹H-MRS). Dietary Cr intake was assessed by 3 d food recalls. Vegetarians had lower dietary Cr intake than omnivores (0·03 (<sc>sd</sc> 0·01) <italic>v.</italic> 1·34 (<sc>sd</sc> 0·62) g/d, respectively; <italic>P</italic>= 0·005). However, vegetarians and omnivores had comparable brain total Cr content (5·999 (<sc>sd</sc> 0·811) <italic>v.</italic> 5·917 (<sc>sd</sc> 0·665) IU, respectively; <italic>P</italic>= 0·77). In conclusion, dietary Cr did not influence brain Cr content in healthy individuals, suggesting that in normal conditions brain is dependent on its own Cr synthesis.</p> </abstract>