Brainstem‐sparing craniospinal irradiation delivered with pencil beam scanning proton therapy. Issue 4 (3rd January 2015)

• Record Type: Journal Article
• Authors: Hill‐Kayser, Christine; Kirk, Maura
• Is Part Of: Pediatric blood & cancer. Volume 62:Issue 4(2015:Apr.)
• Page Start: 718
• Page End: 720
• Publication Date: 2015-01-03
• Subjects: Tumors in children -- Periodicals; Blood -- Diseases -- Periodicals; Cancer in children -- Periodicals; 618.92
• DOI: 10.1002/pbc.25378
• Languages: English
• ISSNs: 1545-5009

Abstract

<abstract abstract-type="main" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="pbc25378-sec-0001" sec-type="section"> <p>Delivery of craniospinal irradiation (CSI) is a curative approach to recurrent ependymoma, but is associated with risks from re‐irradiation, particularly of the brainstem. Pencil beam scanning proton therapy allows delivery of CSI with sparing of normal tissues. Here, we describe a case of brainstem‐sparing CSI that resulted in excellent coverage of the craniospinal axis with minimal radiation to brainstem. This is a novel concept that compares favorably to previously described methods using x‐rays that may result in underdosing of surrounding tissues in effort to spare brainstem. Pediatr Blood Cancer 2015;62:718–720. © 2015 Wiley Periodicals, Inc.</p> </sec> </abstract>