1064 nm long‐pulsed Nd:YAG laser treatment of basal cell carcinoma. Issue 2 (2nd February 2015)

• Record Type: Journal Article
• Authors: Ortiz, Arisa E.; Anderson, R. Rox; Avram, Mathew M.; Avram, Mathew M.; Ortiz, Arisa E.
• Is Part Of: Lasers in surgery and medicine. Volume 47:Issue 2(2015)
• Page Start: 106
• Page End: 110
• Publication Date: 2015-02-02
• Subjects: Lasers in medicine -- Periodicals; Lasers in surgery -- Periodicals; 617
• DOI: 10.1002/lsm.22310
• Languages: English
• ISSNs: 0196-8092

Abstract

<abstract abstract-type="main" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="lsm22310-sec-0001" sec-type="section"> <title>Background and Objective</title> <p>Standard surgical and destructive treatments for basal cell carcinoma (BCC) can result in significant morbidity and scarring, stimulating the investigation of alternative non‐surgical options. The objective of this study was to determine the safety, clinical, and histological efficacy of pulsed, high‐fluence 1064 nm Nd:YAG laser therapy for the treatment of BCC on the trunk and extremities.</p> </sec> <sec id="lsm22310-sec-0002" sec-type="section"> <title>Study Design/Materials and Methods</title> <p>This was a prospective, non‐randomized, open‐label clinical trial. Ten subjects with a biopsy‐proven BCC less than 1.5 cm in diameter on the trunk or extremities received one treatment with a 10 milliseconds pulsed 1064 nm Nd:YAG laser. Standard excision was performed 1 month after laser treatment to confirm histologic clearance.</p> </sec> <sec id="lsm22310-sec-0003" sec-type="section"> <title>Results</title> <p>The laser treatment was quick and well tolerated. There was complete histologic clearance after one treatment in 92% of the BCC tumors, overall. At higher fluences, there was 100% histologic clearance after one treatment. No significant adverse events were seen, including scarring.</p> </sec> <sec id="lsm22310-sec-0004" sec-type="section"> <title>Conclusions</title> <p>The 1064 nm long‐pulsed Nd:YAG laser may offer a safe alternative for treating BCC off the face. A larger study is highly warranted to confirm these preliminary results. Lasers Surg. Med. 47:106–110, 2015. © 2015 Wiley Periodicals, Inc.</p> </sec> </abstract>