Direct arylation of imidazo[2, 1‐b]thiazoles and thiazoles with aryl iodides via CuCl2/PPh3‐catalyzed C–H bond functionalization. (15th January 2015)

• Record Type: Journal Article
• Authors: Ma, Yuchang; Na, Min; Gu, Yanfang; Huang, Guoli; Li, Xia; Chen, Yegao
• Is Part Of: Applied organometallic chemistry. Volume 29:Number 3(2015:Mar.)
• Page Start: 165
• Page End: 169
• Publication Date: 2015-01-15
• Subjects: Organometallic chemistry -- Periodicals; Organometallic compounds -- Periodicals; 547.05
• DOI: 10.1002/aoc.3263
• Languages: English
• ISSNs: 0268-2605

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>With PPh₃ acting as a ligand, a convenient method for CuCl₂‐catalyzed <named-content content-type="reactionType" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">arylation</named-content> of imidazo[1, 2‐<italic>b</italic>]thiazoles and thiazoles with aryl iodides under mild reaction conditions is described. Preliminary mechanistic studies of this <named-content content-type="reactionType" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">arylation</named-content> involving a formal Cu(I) to Cu(0) and Cu(II) route by convergent <named-content content-type="reactionType" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">disproportionation</named-content> of the copper mediator are also reported. Copyright © 2015 John Wiley &amp; Sons, Ltd.</p> </abstract>